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Randomised controlled trial of intravenous magnesium sulfate versus terbutaline for children in the management of acute exacerbation of asthma.

Plain-language guide to PMID 42444205 (2026): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 2024, children.

Key Facts

PMID
42444205
Journal
JPMA. The Journal of the Pakistan Medical Association
Year
2026
Study type
Randomized Controlled Trial
Authors
Zulqarnain A et al. (4 authors)
DOI
10.47391/JPMA.22541
Registered trial
NCT06626620

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Who Took Part

According to the abstract, 2024, children were involved.

The age groups tagged for this paper are young children and children, both men and women.

This randomised controlled trial was conducted at the Paediatric Department of The Children's Hospital and Institute of Child Health, Multan, Pakistan, from January to August 2024, and comprised children of either gender aged 5-12 years who had a history of asthma for a minimum of six months, and presented with acute exacerbation of asthma requiring emergency treatment.

The patients were randomly allocated to group A receiving intravenous magnesium sulfate and group B receiving intravenous terbutaline.

How the Study Was Run

The researchers set it up as a randomized study.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Data was analysed using SPSS 26.

What Was Measured

The subject headings attached to it are Terbutaline, Magnesium Sulfate, Asthma, Peak Expiratory Flow Rate, Bronchodilator Agents, Heart Rate and Pakistan.

Author keywords: Asthma, Heart rate, Peak expiratory flow rate, Respiratory rate, Terbutaline.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 2024, children.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (JPMA. The Journal of the Pakistan Medical Association), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.