The Role of Vitamin D in Plastic and Reconstructive Surgery: A Systematic Review of Human and Animal Studies.

What It Covers

This systematic review looks at Vitamin D, K2, Magnesium and Zinc.

To systematically review the existing literature on the impact of preoperative and perioperative vitamin D levels on surgical outcomes in plastic and reconstructive surgery, combining findings from both animal and human studies.

Why It Was Studied

Its deficiency is a global public health concern, affecting postoperative outcomes across various surgical fields, including plastic and reconstructive surgery.

Who the Included Studies Covered

Inclusion criteria encompassed human and animal studies examining the role of vitamin D in wound healing, aesthetic procedures, reconstructive surgeries, nerve regeneration, and orthognathic interventions.

Data extraction and quality assessment were performed using standardized tools.

How the Review Was Done

A detailed literature search was conducted in Embase, PubMed, Ovid Medline, PubMed Central, Scopus, and Cochrane Central databases.

A structured sensitivity analysis by study design and quality was also performed.

What Was Measured

Its deficiency is a global public health concern, affecting postoperative outcomes across various surgical fields, including plastic and reconstructive surgery.

Topics PubMed links to this paper include Plastic Surgery Procedures, Wound Healing, Vitamin D, Vitamin D Deficiency and Postoperative Complications.

The authors tagged it with the keywords aesthetic surgery, nerve regeneration, orthognathic surgery and reconstructive surgeries.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (Annals of plastic surgery), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.