Metabolic effects of growth hormone administered subcutaneously once or twice daily to growth hormone deficient adults.

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The actions of GH might depend upon a pulsatile pattern of serum GH.

Pulsatile and continuous intravenous delivery of GH, however, induce similar short-term metabolic effects in GH deficient patients.

Who Took Part

The abstract describes 8 patients taking part.

The age groups tagged for this paper are teenagers and adults, both men and women.

How the Study Was Run

The design is described as randomized and crossover.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

Each person switched between Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and the comparison at some point, usually with a gap in between.

What Was Measured

The subject headings attached to it are Blood Glucose, Carrier Proteins, Fatty Acids, Nonesterified, Growth Disorders, Growth Hormone, Insulin and Insulin-Like Growth Factor Binding Proteins.

What This Means in Plain Language

The paper is a randomized and crossover study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 8 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1994 (Clinical endocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.