A new system for fallopian tube sperm perfusion leads to pregnancy rates twice as high as standard intrauterine insemination.

What Was Tested

Researchers studied Clomiphene in this randomized controlled trial publication.

Who Took Part

The abstract describes 74 women taking part.

By PubMed's age tags, the people studied were adults, women only.

Ovulation induction program of a tertiary outpatient care center, Hôpital Antoine Béclère, Clamart, France.

Thirty-six hours after hCG administration, patients were assigned randomly to either IUI (group A, n = 50) or fallopian tube sperm perfusion (group B, n = 50).

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Clomiphene and who got the comparison, which limits bias.

Controlled ovarian hyperstimulation was achieved using three types of ovarian stimulation protocols: clomiphene citrate (CC) and hMG (n = 35). hMG alone (n = 35) or GnRH agonist and FSH and hMG (n = 30).

What Was Measured

PubMed files the paper under topics including Clomiphene, Fallopian Tubes, Follicle Stimulating Hormone, Infertility, Female, Insemination, Artificial, Menotropins and Ovulation Induction.

What This Means in Plain Language

The paper is a randomized study of Clomiphene in 74 women.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1995 (Fertility and sterility), a journal based in United States.

More context: all human trials.