The effects of gonadotrophin-releasing hormone agonists on iliac crest cancellous bone structure in women with endometriosis

What Was Tested

This randomized controlled trial paper looks at Goserelin and Triptorelin in the context of endometriosis.

The administration of gonadotrophin-releasing hormone (GnRH) analogs to premenopausal women causes hypoestrogenism and bone loss, but the effects on cancellous microstructure have not been determined.

In this study the researchers have assessed bone structure in transiliac biopsies obtained from women before and after treatment for endometriosis with GnRH analogs.

Who Took Part

PubMed indexes the participants as adults, women only.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Goserelin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

In this study the researchers have assessed bone structure in transiliac biopsies obtained from women before and after treatment for endometriosis with GnRH analogs.

Topics PubMed links to this paper include Anabolic Agents, Biopsy, Bone Density, Bone Resorption, Endometriosis, Gonadotropin-Releasing Hormone and Goserelin.

What This Means in Plain Language

The paper is a randomized study of Goserelin and Triptorelin in people with endometriosis.

The publication is from 1995 (Bone), a journal based in United States.

More context: the Goserelin compound page and the Triptorelin compound page, Endometriosis research.