Gonadotropin requirements of the developing follicle.

What Was Tested

Researchers studied Chorionic Gonadotropin in this randomized controlled trial publication.

To evaluate follicular FSH and LH requirements during suppression of endogenous gonadotropins with the GnRH antagonist Nal-Glu and whether LH-like activity could be supplied by administering subcutaneous hCG.

Who Took Part

According to the abstract, 11 subjects were involved.

By PubMed's age tags, the people studied were adults, women only.

Subjects returned the next day for repeat blood sample and ultrasound.

How the Study Was Run

The design is described as randomized.

The subjects were allocated by chance, so the Chorionic Gonadotropin group and the comparison group should start out alike.

Thirty-two normally cycling females in the late follicular phase (dominant follicle mean diameter > or = 14 mm).

What Was Measured

The subject headings attached to it are Chorionic Gonadotropin, Estradiol, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Luteinizing Hormone and Menotropins.

What This Means in Plain Language

The paper is a randomized study of Chorionic Gonadotropin in 11 subjects.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1995 (Fertility and sterility), a journal based in United States.

More context: the related hCG (human chorionic gonadotropin) library page, all human trials.