Comparison between prolactin, gonadotrophins and steroid hormones in serum and follicular fluid after stimulation with gonadotrophin-releasing hormone agonists and human menopausal gonadotrophin for an in-vitro fertilization programme.

What Was Tested

This randomized controlled trial looks at Chorionic Gonadotropin.

The inter-relationship between serum and follicular fluid prolactin, oestradiol, progesterone, follicle stimulating hormone (FSH), and luteinizing hormone (LH) in two groups of women was investigated.

In group 2, 25 women were simultaneously stimulated with GnRH-a in a short protocol with HMG.

Who Took Part

According to the abstract, 32 women were involved.

The age groups tagged for this paper are adults, both men and women.

In group 1, 32 women were treated with gonadotrophin-releasing hormone agonist (GnRH-a) in a long term protocol and subsequently stimulated with human menopausal gonadotrophin (HMG).

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Chorionic Gonadotropin and who got the comparison, which limits bias.

What Was Measured

PubMed files the paper under topics including Chorionic Gonadotropin, Estradiol, Fertilization in Vitro, Follicle Stimulating Hormone, Follicular Fluid, Gonadotropins, Pituitary and Luteinizing Hormone.

What This Means in Plain Language

The paper is a randomized study of Chorionic Gonadotropin in 32 women.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1994 (Human reproduction (Oxford, England)), a journal based in England.

More context: the related hCG (human chorionic gonadotropin) library page, all human trials.