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Cardiac performance and mass in adults with hypopituitarism: effects of one year of growth hormone treatment.

Plain-language guide to PMID 7852533 (1995): controlled clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 20 patients.

Key Facts

PMID
7852533
Journal
The Journal of clinical endocrinology and metabolism
Year
1995
Study type
Controlled Clinical Trial
Authors
Valcavi R et al. (6 authors)
DOI
10.1210/jcem.80.2.7852533

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a controlled clinical trial.

M- and B-mode echocardiography and pulsed Doppler examination of transmitral flow were performed before treatment, 6 months and 1 yr after starting GH or placebo administration, and 15 days and 3 months after GH or placebo withdrawal.

Twenty healthy subjects, matched for age, sex, body mass index, and physical activity, served as controls.

Who Took Part

According to the abstract, 20 patients were involved.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as placebo-controlled.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Body Mass Index, Body Surface Area, Echocardiography, Growth Hormone, Heart and Heart Rate.

What This Means in Plain Language

The paper is a placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 20 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1995 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.