[Magnesium in migraine. Results of a multicenter pilot study].

What Was Tested

This randomized controlled trial looks at Citrates in the context of migraine.

With the aim of testing this hypothesis, a doubleblind, cross-over multicenter pilot study was initiated.

Why It Was Studied

Numerous experiments and clinical observations have credited magnesium with a positive influence on the incidence of migraine attacks.

Who Took Part

The abstract describes 43 patients taking part.

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

The study contained 43 migraine patients who met the criteria of the international Headache Society.

How the Study Was Run

The design is described as randomized, double-blind, crossover, multicenter and pilot.

The patients were allocated by chance, so the Citrates group and the comparison group should start out alike.

Neither the patients nor the staff measuring them knew who was on Citrates, so expectations could not easily colour the readings.

Each person switched between Citrates and the comparison at some point, usually with a gap in between.

Running at several centres spread the Citrates study over different clinics and patient groups.

What Was Measured

The subject headings attached to it are Citrates, Citric Acid, Family Practice, Migraine Disorders and Pilot Projects.

What This Means in Plain Language

The paper is a randomized, double-blind and crossover study of Citrates in 43 patients in people with migraine.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 1994 (Fortschritte der Medizin), a journal based in Germany.

More context: Migraine research.