Effect of magnesium on restenosis after percutaneous transluminal coronary angioplasty: a clinical and angiographic evaluation in a randomized patient population. A pilot study. The Ichilov Magnesium Study Group.

What Was Tested

Researchers studied Magnesium and Magnesium Hydroxide in this randomized controlled trial publication.

Restenosis is a major clinical problem following successful percutaneous transluminal coronary angioplasty.

In an open-labelled, randomized controlled study, 148 patients underwent successful coronary angioplasty.

Who Took Part

According to the abstract, 148 patients were involved.

By PubMed's age tags, the people studied were teenagers, adults, middle-aged adults, older adults and people over 80, both men and women.

How the Study Was Run

In design terms this was a randomized, open-label and pilot study.

Random assignment meant chance, not the researchers, decided who got Magnesium and who got the comparison, which limits bias.

Everyone knew when Magnesium was being given (open label), which is simpler to run but leaves more room for expectations to affect what is reported.

It is described as a pilot, a small early test of whether a larger Magnesium study would be practical.

What Was Measured

Clinical, laboratory, ergometric and radionuclide evaluations were also carried out.

PubMed files the paper under topics including Angioplasty, Balloon, Coronary, Coronary Disease, Magnesium, Magnesium Hydroxide, Magnesium Sulfate, Observer Variation and Patient Compliance.

What This Means in Plain Language

The paper is a randomized, open-label and pilot study of Magnesium and Magnesium Hydroxide in 148 patients.

The publication is from 1994 (European heart journal), a journal based in England.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.