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Recombinant human growth hormone accelerates wound healing in children with large cutaneous burns.

Plain-language guide to PMID 8024354 (1994): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
8024354
Journal
Annals of surgery
Year
1994
Study type
Randomized Controlled Trial
Authors
Gilpin DA et al. (5 authors)
DOI
10.1097/00000658-199407000-00004

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Two forms of recombinant growth hormone that accelerate the healing of skin graft donor sites in severely burned children were evaluated.

Why It Was Studied

Through genetic engineering, several different forms have been synthesized; however, not all are marketed currently.

Who Took Part

By PubMed's age tags, the people studied were infants, young children, children and teenagers, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Exogenous HGH, sermorelin & older GHRPs (why they're passed over), so expectations could not easily colour the readings.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

The initial donor site healing time, in days, was reached when the gauze could be removed without any trauma to the healed site.

What Was Measured

Topics PubMed links to this paper include Age Factors, Burns, Combined Modality Therapy, Dermatologic Surgical Procedures, Growth Hormone, Hormones and Human Growth Hormone.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1994 (Annals of surgery), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.