Changes in glucose turnover parameters and improvement of glucose oxidation after 4-week magnesium administration in elderly noninsulin-dependent (type II) diabetic patients.

What Was Tested

The paper reports a study of Magnesium, published as a randomized controlled trial.

The aim of the present study was to investigate the effects of magnesium supplementation on glucose uptake and substrate oxidation in noninsulin-dependent (type II) diabetic patients.

Why It Was Studied

Nine elderly non-obese noninsulin-dependent (type II) diabetic patients, treated by diet only, participated in the study, which was designed as randomized, double blind, and cross-over.

Who Took Part

By PubMed's age tags, the people studied were older adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and crossover.

Because people in this Magnesium study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Magnesium study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Magnesium could be set against what happens without it.

Each person switched between Magnesium and the comparison at some point, usually with a gap in between.

What Was Measured

PubMed files the paper under topics including Blood Glucose, C-Peptide, Diabetes Mellitus, Type 2, Erythrocytes, Glucagon, Glucose and Insulin.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Magnesium.

The publication is from 1994 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.