Influence of oral magnesium supplementation on cardiac events among survivors of an acute myocardial infarction.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To investigate the effect of long term oral magnesium treatment on incidence of cardiac events among survivors of an acute myocardial infarction.

Who Took Part

According to the abstract, 289 men were involved.

By PubMed's age tags, the people studied were adults, middle-aged adults, older adults and people over 80, both men and women.

Double blind, placebo controlled parallel study in which patients were randomised to treatment or placebo.

Two coronary care units and corresponding outpatient clinics.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and parallel-group.

The men were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Neither the men nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

468 survivors of an acute myocardial infarction (289 men and 178 women) aged 31-92.

What Was Measured

Topics PubMed links to this paper include Coronary Artery Bypass, Death, Sudden, Cardiac, Long-Term Care, Magnesium Hydroxide, Myocardial Infarction, Recurrence and Risk Factors.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 289 men.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1993 (BMJ (Clinical research ed.)), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.