The relationship between early plasma atrial natriuretic factor levels and exercise performance after myocardial infarction

What Was Tested

This randomized controlled trial paper looks at ANP (Atrial Natriuretic Peptide).

The researchers tested the hypothesis that early plasma atrial natriuretic factor (ANF) values are related to subsequent functional capacity in patients with acute myocardial infarction (MI).

Blood for ANF determination was sampled from 90 male patients (age 66.5 +/- 9.5 (mean +/- SD) years) day 3 post MI.

Who Took Part

The study group was 90 patients.

The age groups tagged for this paper are middle-aged adults and older adults, men only.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this ANP (Atrial Natriuretic Peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind ANP (Atrial Natriuretic Peptide) study, the assignments were hidden from both participants and investigators until the end.

What Was Measured

The researchers tested the hypothesis that early plasma atrial natriuretic factor (ANF) values are related to subsequent functional capacity in patients with acute myocardial infarction (MI).

Exercise testing on an upright bicycle ergometer to symptomatic end-points was performed 1 and 6 months after MI in 83 and 78 patients, respectively.

PubMed files the paper under topics including Atrial Natriuretic Factor, Creatine Kinase, Enalapril, Exercise Test, Hemodynamics, Isoenzymes and Myocardial Contraction.

What This Means in Plain Language

The paper is a randomized and double-blind study of ANP (Atrial Natriuretic Peptide) in 90 patients.

The publication is from 1993 (European heart journal), a journal based in England.

More context: the ANP (Atrial Natriuretic Peptide) compound page, all human trials.