← Human Trials & Peer-Reviewed Studies
The influence of growth hormone (rhGH) therapy on tooth formation in idiopathic short statured children.
Plain-language guide to PMID 8480701 (1993): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
Key Facts
- PMID
- 8480701
- Journal
- American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
- Year
- 1993
- Study type
- Randomized Controlled Trial
- Authors
- Ito RK et al. (8 authors)
- DOI
- 10.1016/0889-5406(93)70017-I
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.
The purpose of this preliminary study was to evaluate tooth formation in children with idiopathic short stature, before and during treatment with recombinant growth hormone (rhGH).
Why It Was Studied
Clinical and radiographic records were obtained at the initial, year 1, and year 2 visits.
Delta-Z scores, which measure the change in Z-score over time, were also calculated between annual visits.
Who Took Part
PubMed indexes the participants as children and teenagers, both men and women.
Tooth formation and stature were assessed by calculating Z-scores, appropriate for the age and gender of each child.
How the Study Was Run
In design terms this was a randomized study.
The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.
Height was measured and recorded every 3 months, and Z-score statural norms for age and gender were derived from the 1977 National Center for Health Services national probability sampling.
What Was Measured
Delta-Z scores, which measure the change in Z-score over time, were also calculated between annual visits.
PubMed files the paper under topics including Age Determination by Skeleton, Body Height, Dwarfism, Growth Disorders, Growth Hormone, Odontogenesis and Reproducibility of Results.
What This Means in Plain Language
The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
The publication is from 1993 (American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics), a journal based in United States.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.