The effect of gonadotropin-releasing hormone agonist on embryo quality and pregnancy rate following cryopreservation.

What Was Tested

This clinical trial looks at Gonadotropin-Releasing Hormone.

To examine the effect of GnRH analogue (GnRH-a) on the quality of frozen-thawed embryos and the pregnancy rate (PR) resulting from transfer.

Who Took Part

The study group was 108 women.

The age groups tagged for this paper are adults, women only.

A retrospective study of two groups of women undergoing transfers of frozen-thawed embryos.

The study group (group 1) included 108 women who underwent 137 transfer cycles of frozen-thawed embryos, and the control group (group 2) included 44 women in 51 cycles of thawed ETs.

How the Study Was Run

In group 2 ovulation was induced with hMG only.

The freezing and thawing techniques were identical for both groups.

In vitro fertilization unit at a university hospital.

Ovum pick-up and ET techniques were the same for both groups.

Methods of embryo freezing and thawing were identical, as were the morphological criteria for grading the embryos.

What Was Measured

Topics PubMed links to this paper include Abortion, Spontaneous, Blastomeres, Cryopreservation, Embryo Transfer, Embryo, Mammalian, Fertilization and Fertilization in Vitro.

What This Means in Plain Language

This is a clinical trial of Gonadotropin-Releasing Hormone in 108 women.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 1993 (Fertility and sterility), a journal based in United States.

More context: all human trials.