← Human Trials & Peer-Reviewed Studies
Recombinant growth hormone treatment of amyotrophic lateral sclerosis.
Plain-language guide to PMID 8502260 (1993): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 75 patients.
Key Facts
- PMID
- 8502260
- Journal
- Muscle & nerve
- Year
- 1993
- Study type
- Randomized Controlled Trial
- Authors
- Smith RA et al. (6 authors)
- DOI
- 10.1002/mus.880160608
What This Study Did, in Plain Language
What Was Tested
Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.
Hyperglycemia was noted in only 2 patients of the 38 patients receiving hGH, and this resolved with cessation of treatment.
Who Took Part
According to the abstract, 75 patients were involved.
The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.
Neither the patients nor the staff measuring them knew who was on Exogenous HGH, sermorelin & older GHRPs (why they're passed over), so expectations could not easily colour the readings.
A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.
The course of ALS was assessed serially using a quantitative (TQNE) neuromuscular and manual exam (MRC) and laboratory chemistries.
What Was Measured
The subject headings attached to it are Amyotrophic Lateral Sclerosis, Cohort Studies, Growth Hormone, Human Growth Hormone, Insulin-Like Growth Factor I, Recombinant Proteins and Survival Analysis.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 75 patients.
The publication is from 1993 (Muscle & nerve), a journal based in United States.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.