Gamete intra-Fallopian transfer or in-vitro fertilization after failed ovarian stimulation and intrauterine insemination in unexplained infertility?

What Was Tested

The paper reports a study of Buserelin, published as a randomized controlled trial.

A prospective randomized study was designed to compare gamete intra-Fallopian transfer (GIFT) and in-vitro fertilization (IVF) and embryo transfer in the treatment of couples who have failed to conceive after at least three cycles of ovarian stimulation and intrauterine insemination (IUI).

Why It Was Studied

A total of 69 couples with primary unexplained infertility of at least 2 years' duration plus at least three failed cycles of ovarian stimulation and IUI were randomly allocated to either GIFT or IVF/embryo transfer.

Who Took Part

The age groups tagged for this paper are adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Buserelin group and the comparison group should start out alike.

What Was Measured

A total of 69 couples with primary unexplained infertility of at least 2 years' duration plus at least three failed cycles of ovarian stimulation and IUI were randomly allocated to either GIFT or IVF/embryo transfer.

The subject headings attached to it are Buserelin, Chorionic Gonadotropin, Embryo Transfer, Fertilization in Vitro, Gamete Intrafallopian Transfer, Insemination, Artificial, Homologous and Ovulation Induction.

What This Means in Plain Language

The paper is a randomized study of Buserelin.

The publication is from 1995 (Human reproduction (Oxford, England)), a journal based in England.

More context: all human trials.