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Ethanol decreases nocturnal plasma levels of thyrotropin and growth hormone but not those of thyroid hormones or prolactin in man.

Plain-language guide to PMID 8675588 (1996): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 0100 subjects.

Key Facts

PMID
8675588
Journal
The Journal of clinical endocrinology and metabolism
Year
1996
Study type
Randomized Controlled Trial
Authors
Ekman AC et al. (6 authors)
DOI
10.1210/jcem.81.7.8675588

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

Previous studies on the effects of ethanol on circulating pituitary hormones have been carried out mostly during daytime when the secretion of these hormones is generally at a nadir.

The plasma PRL profile was not affected by ethanol.

Who Took Part

According to the abstract, 0100 subjects were involved.

The age groups tagged for this paper are adults, both men and women.

How the Study Was Run

In design terms this was a randomized, double-blind and crossover study.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

Blinding on both sides kept the subjects and researchers unaware of who received Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Each person switched between Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and the comparison at some point, usually with a gap in between.

Plasma GHRH was measured after solid phase separation in RIA, but it did not show any ethanol-related changes.

What Was Measured

PubMed files the paper under topics including Circadian Rhythm, Ethanol, Growth Hormone, Prolactin, Thyroid Hormones, Thyrotropin and Thyrotropin-Releasing Hormone.

What This Means in Plain Language

The paper is a randomized, double-blind and crossover study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 0100 subjects.

The publication is from 1996 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.