The 24-hour rhythms in plasma growth hormone, prolactin and thyroid stimulating hormone: effect of sleep deprivation.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this clinical trial publication.

Twenty-four hour secretory rhythms of growth hormone (GH), prolactin (PRL) and thyroid stimulating hormone (TSH) were investigated in 9 normal adult men by means of serial blood sampling at 30 min intervals.

The profiles of pituitary hormones were compared in 6 subjects between in normal nocturnal sleep condition and in delayed sleep condition.

Who Took Part

According to the abstract, 9 men were involved.

The age groups tagged for this paper are adults, men only.

How the Study Was Run

Plasma GH was measured with use of highly sensitive enzyme immunoassay (EIA) recently developed.

What Was Measured

Plasma TSH was also evaluated by highly sensitive time-resolved fluorometric immunoassay (TR-FIA).

The detection limit of EIA for GH was 0.3 pg/ml and all plasma GH levels were within the detectable range of this EIA.

PubMed files the paper under topics including Activity Cycles, Circadian Rhythm, Fluorescent Antibody Technique, Growth Hormone, Prolactin, Sleep Deprivation and Sleep, REM.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 9 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1995 (Journal of neuroendocrinology), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.