Comparison of methods to estimate body fat in growth hormone deficient adults.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.

All of the presently used methods for in-vivo determination of body composition have inherent methodological errors and depend on various assumptions.

The researchers have therefore compared several different methods used to measure body fat in adult GH deficiency during GH treatment.

Who Took Part

The study group was 23 patients.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

Twenty-five patients with known GH deficiency entered the study.

Baseline examinations were complete in 23 patients, and 22 patients (16 males, 6 females) completed all examinations after treatment.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Neither the patients nor the staff measuring them knew who was on Exogenous HGH, sermorelin & older GHRPs (why they're passed over), so expectations could not easily colour the readings.

Some patients received a placebo instead of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), giving a reference point.

Body fat calculated from total body potassium (TBK) by whole-body 40K counting, total body water (TBW) by tritium dilution, total body nitrogen (TBN) by neutron activation, and bioelectric impedance (BIA) measurements were compared to body fat determinations by dual-energy X-ray absorptiometry (DEXA) in two-compartment and multicompartment body composition models.

What Was Measured

The subject headings attached to it are Absorptiometry, Photon, Adipose Tissue, Body Composition, Body Water, Electric Impedance, Growth Hormone and Models, Biological.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 23 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 1996 (Clinical endocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.