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Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double-blind crossover field study
Plain-language guide to PMID 8803503 (1996): double-blind randomized controlled trial study of L-Carnitine.
Key Facts
- PMID
- 8803503
- Journal
- European journal of applied physiology and occupational physiology
- Year
- 1996
- Study type
- Randomized Controlled Trial
- Authors
- Colombani P et al. (9 authors)
- DOI
- 10.1007/BF00334420
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of L-Carnitine, published as a randomized controlled trial.
A double-blind crossover field study was performed to investigate the effects of acute L-carnitine supplementation on metabolism and performance of endurance-trained athletes during and after a marathon run.
Why It Was Studied
The plasma concentration of metabolites and hormones was analysed 1 h before, immediately after and 1 h after the run, as well as the next morning after the run.
In addition, the respiratory exchange ratio (R) was determined before and at the end of the run, and a submaximal performance test was completed on a treadmill the morning after the run.
Who Took Part
PubMed indexes the participants as adults and middle-aged adults, men only.
How the Study Was Run
The design is described as randomized, double-blind and crossover.
Because people in this L-Carnitine study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Blinding on both sides kept the participants and researchers unaware of who received L-Carnitine.
In the crossover set-up each of the participants took both L-Carnitine and the comparison in turn, acting as their own control.
What Was Measured
In addition, the respiratory exchange ratio (R) was determined before and at the end of the run, and a submaximal performance test was completed on a treadmill the morning after the run.
Topics PubMed links to this paper include Carbohydrates, Carnitine, Energy Metabolism, Enzymes, Exercise Test, Hormones and Oxygen Consumption.
What This Means in Plain Language
The paper is a randomized, double-blind and crossover study of L-Carnitine.
The publication is from 1996 (European journal of applied physiology and occupational physiology), a journal based in Germany.
More context: the L-Carnitine compound page, all human trials.
Our Notes on the Compound
L-Carnitine: An amino acid derivative that carries fatty acids into mitochondria for energy production.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.