Cognitive impairments and mood disturbances in growth hormone deficient men.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this clinical trial publication.

Assessments included evaluation of somatic and psychological complaints, depression, fatigue, vigor, tension, state and trait anxiety, iconic memory, short-term memory, long-term memory and perceptual-motor skill.

The control group consisted of 41 healthy men, matched for age.

Who Took Part

According to the abstract, 31 men were involved.

PubMed indexes the participants as teenagers and adults, both men and women.

In order to establish whether reported psychological complaints in hypopituitary adults are related to growth hormone (GH) deficiency or other pituitary hormone deficiencies, emotional well-being and cognitive performance were evaluated in 31 men with multiple pituitary hormone deficiencies (MPHD) and in 17 men with isolated growth hormone deficiency (IGHD).

What Was Measured

Assessments included evaluation of somatic and psychological complaints, depression, fatigue, vigor, tension, state and trait anxiety, iconic memory, short-term memory, long-term memory and perceptual-motor skill.

Despite oral replacement therapy, MPHD patients also had lower serum testosterone levels than IGHD subjects.

Topics PubMed links to this paper include Affect, Anxiety, Cognition Disorders, Education, Growth Hormone, Intelligence Tests and Memory.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 31 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1996 (Psychoneuroendocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.