Progesterone alone versus progesterone combined with HCG as luteal support in GnRHa/HMG induced IVF cycles: a randomized clinical trial.

What Was Tested

Researchers studied Chorionic Gonadotropin and Progesterone in this randomized controlled trial publication.

The primary aim of this study was to assess the effect of the different regimens of luteal support on the pregnancy rate.

The secondary aim was to compare oestradiol and progesterone concentrations in the luteal phase between the two groups, and assess their effect on the pregnancy rate.

Why It Was Studied

Two different regimens of luteal support in gonadotrophin hormone-releasing hormone (GnRH) analogue/human menopausal gonadotrophin (GnRHa/HMG)-induced in-vitro fertilization cycle (IVF) were compared in a randomized clinical trial.

After embryo transfer, either vaginal progesterone alone was administered (n = 89, P group), or a combination of vaginal progesterone and human chorionic gonadotrophin (n = 87, P/HCG group).

Who Took Part

The age groups tagged for this paper are adults, women only.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Chorionic Gonadotropin group and the comparison group should start out alike.

What Was Measured

The subject headings attached to it are Chorionic Gonadotropin, Drug Combinations, Estradiol, Fertilization in Vitro, Gonadotropin-Releasing Hormone, Luteal Phase and Menotropins.

What This Means in Plain Language

The paper is a randomized study of Chorionic Gonadotropin and Progesterone.

The publication is from 1996 (Human reproduction (Oxford, England)), a journal based in England.

More context: the related hCG (human chorionic gonadotropin) library page, all human trials.