[Relationship between fasting glycemia, serum peptide C, insulin, growth hormone and plasma glucagon in acromegaly]

What Was Tested

Researchers studied Glucagon in this controlled clinical trial publication.

The aim of this study was to investigate interrelations among fasting glycaemia, serum C-peptide, insulin, growth hormone and plasma glucagon concentration in people with acromegaly. 22 patients with active acromegaly, 11 women and 11 men (group A) and 19 healthy people (group K) participated in the study.

Why It Was Studied

The oral glucose tolerance test was carried out in all participants.

Statistical analysis was performed using Student's test and regression analysis.

Who Took Part

The abstract describes 22 patients taking part.

By PubMed's age tags, the people studied were children, teenagers, adults, middle-aged adults and older adults, both men and women.

Blood glucose, serum C-peptide, growth hormone and plasma glucagon concentration was measured. 13 patients with acromegaly had normal glucose tolerance (group AT) and 9 had impaired glucose tolerance (group AN).

What Was Measured

The oral glucose tolerance test was carried out in all participants.

Statistical analysis was performed using Student's test and regression analysis.

Topics PubMed links to this paper include Acromegaly, Blood Glucose, C-Peptide, Fasting, Glucagon, Hormones and Human Growth Hormone.

What This Means in Plain Language

This is a controlled clinical trial of Glucagon in 22 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1996 (Polskie Archiwum Medycyny Wewnetrznej), a journal based in Poland.

More context: the Glucagon compound page, all human trials.