Effects of a yeast-based dietary supplementation on premenstrual syndrome. A double-blind placebo-controlled study.

What Was Tested

This randomized controlled trial looks at Magnesium.

In this double-blind, placebo-controlled study, the researchers evaluated the effects of a new dietetic preparation (Sillix Donna, Giuliani) in 40 patients affected by mild to moderate premenstrual syndrome.

Premenstrual symptoms were scored in both follicular and luteal phases, at baseline, at 2nd, 4th and 6th month of treatment by using the Menstrual Distress Questionnaire (MDQ).

Who Took Part

According to the abstract, 40 patients were involved.

The age groups tagged for this paper are adults, women only.

Twenty patients were randomised to receive the active preparation and 20 placebo.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Magnesium study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the patients nor the staff measuring them knew who was on Magnesium, so expectations could not easily colour the readings.

Some patients received a placebo instead of Magnesium, giving a reference point.

What Was Measured

In this double-blind, placebo-controlled study, the researchers evaluated the effects of a new dietetic preparation (Sillix Donna, Giuliani) in 40 patients affected by mild to moderate premenstrual syndrome.

Premenstrual symptoms were scored in both follicular and luteal phases, at baseline, at 2nd, 4th and 6th month of treatment by using the Menstrual Distress Questionnaire (MDQ).

PubMed files the paper under topics including Food, Fortified, Magnesium, Premenstrual Syndrome, Saccharomyces cerevisiae and Surveys and Questionnaires.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Magnesium in 40 patients.

The publication is from 1997 (Gynecologic and obstetric investigation), a journal based in Switzerland.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.