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Vasopressin and oxytocin levels during normal pregnancy: effects of chronic dietary sodium restriction
Plain-language guide to PMID 9071954 (1997): randomized controlled trial study of Oxytocin and Vasopressin.
Key Facts
- PMID
- 9071954
- Journal
- The Journal of endocrinology
- Year
- 1997
- Study type
- Randomized Controlled Trial
- Authors
- van der Post JA et al. (9 authors)
- DOI
- 10.1677/joe.0.1520345
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Oxytocin and Vasopressin, published as a randomized controlled trial.
Neurohypophysial hormones are thought to be involved in alterations in fluid balance during pregnancy and delivery.
In the present study, the researchers measured the effect of long-term severe sodium restriction on vasopressin (AVP) and oxytocin (OT) levels during normal pregnancy and after delivery.
Who Took Part
PubMed indexes the participants as adults, women only.
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
The methods mention a period of 36 weeks.
What Was Measured
In the present study, the researchers measured the effect of long-term severe sodium restriction on vasopressin (AVP) and oxytocin (OT) levels during normal pregnancy and after delivery.
Circulating plasma levels and urinary excretion of AVP and OT, their neurophysins (Np-AVP and Np-OT) and AVP bound to platelets were determined at regular intervals during pregnancy and after delivery.
PubMed files the paper under topics including Analysis of Variance, Arginine Vasopressin, Blood Platelets, Diet, Sodium-Restricted, Neurophysins, Oxytocin and Postpartum Period.
What This Means in Plain Language
The paper is a randomized study of Oxytocin and Vasopressin over 36 weeks.
The publication is from 1997 (The Journal of endocrinology), a journal based in England.
More context: the Oxytocin compound page and the Vasopressin compound page, all human trials.
Our Notes on the Compounds
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Vasopressin: A 9-amino-acid hormone (antidiuretic hormone) that controls water balance and blood vessel tone; used in septic shock.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.