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The effect of magnesium sulfate therapy on the duration of labor in women with mild preeclampsia at term: a randomized, double-blind, placebo-controlled trial.

Plain-language guide to PMID 9077617 (1997): double-blind randomized controlled trial of Magnesium Sulfate and Oxytocin.

Key Facts

PMID
9077617
Journal
American journal of obstetrics and gynecology
Year
1997
Study type
Randomized Controlled Trial
Authors
Witlin AG et al. (3 authors)
DOI
10.1016/s0002-9378(97)70558-1

What This Study Did, in Plain Language

What Was Tested

Researchers studied Magnesium Sulfate and Oxytocin in this randomized controlled trial publication.

The primary outcome was to determine whether magnesium sulfate therapy prolongs the duration of labor in women with mild preeclampsia.

Who Took Part

PubMed indexes the participants as adults, women only.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Because people in this Magnesium Sulfate study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Magnesium Sulfate, so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Magnesium Sulfate group a baseline to be compared against.

What Was Measured

The subject headings attached to it are Disease Progression, Labor, Obstetric, Magnesium Sulfate, Oxytocin, Postpartum Hemorrhage and Pre-Eclampsia.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Magnesium Sulfate and Oxytocin.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1997 (American journal of obstetrics and gynecology), a journal based in United States.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.