Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy.

What Was Tested

The paper reports a study of Zinc, published as a randomized controlled trial.

The aim of the present study was to determine whether the use of a dentifrice and oral rinse containing sanguinaria extract led to a more rapid resolution of gingival inflammation following initial therapy.

Why It Was Studied

Thirty-four subjects, randomly assigned to one of two treatment groups, took part in this randomized double-blind parallel study.

All subjects received initial therapy including oral hygiene instruction and scaling and root planing as required.

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and parallel-group.

Because people in this Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Zinc.

A placebo (an inactive look-alike) gave the Zinc group a baseline to be compared against.

The Zinc group and the comparison group ran side by side rather than switching.

What Was Measured

PubMed files the paper under topics including Alkaloids, Benzophenanthridines, Dental Plaque, Dental Plaque Index, Dental Scaling, Dentifrices and Gingivitis.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Zinc.

The publication is from 1997 (Australian dental journal), a journal based in Australia.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.