← Human Trials & Peer-Reviewed Studies

Comparison of fallopian tube sperm perfusion with intrauterine insemination in the treatment of infertility.

Plain-language guide to PMID 9130904 (1997): randomized controlled trial of Clomiphene in 50 patients.

Key Facts

PMID
9130904
Journal
Fertility and sterility
Year
1997
Study type
Randomized Controlled Trial
Authors
Nuojua-Huttunen S et al. (5 authors)
DOI
10.1016/s0015-0282(97)81411-2

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Clomiphene, published as a randomized controlled trial.

Who Took Part

According to the abstract, 50 patients were involved.

PubMed indexes the participants as adults, both men and women.

One hundred infertile women with unexplained factor, minimal to mild endometriosis, mild male factor, or ovarian dysfunction, undergoing 50 IUI and 50 fallopian tube sperm perfusion cycles stimulated by clomiphene citrate and hMG.

Thirty-six hours after hCG administration, patients were randomized to either the IUI group (group 1, 50 patients and cycles) or the fallopian tube sperm perfusion group (group 2, 50 patients and cycles).

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Clomiphene and who got the comparison, which limits bias.

The infertility units of the University Central Hospital and the Family Federation of Finland, Oulu, Finland.

What Was Measured

The subject headings attached to it are Clomiphene, Fallopian Tubes, Infertility, Insemination, Artificial, Homologous, Menotropins and Perfusion.

What This Means in Plain Language

The paper is a randomized study of Clomiphene in 50 patients.

Results are reported in around 3 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 1997 (Fertility and sterility), a journal based in United States.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.