Persistence of defective serotonergic and GABAergic controls of growth hormone secretion in long-term abstinent alcoholics.

What Was Tested

This controlled clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Furthermore, tests with GH-releasing hormone (GHRH) and L-arginine (which releases GH from somatostatin inhibition) were performed to determine whether GH secretion in response to its major determinants is preserved in alcoholics.

Why It Was Studied

All subjects were also tested with placebos.

Administration of placebo did not change plasma GH levels in any subject.

Who Took Part

According to the abstract, 12 men were involved.

PubMed indexes the participants as adults and middle-aged adults, men only.

How the Study Was Run

The design is described as placebo-controlled.

A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.

What Was Measured

All subjects were also tested with placebos.

Administration of placebo did not change plasma GH levels in any subject.

The subject headings attached to it are Alcoholism, Human Growth Hormone, Long-Term Care, Serotonin, Serotonin Receptor Agonists, Sodium Oxybate and Sumatriptan.

What This Means in Plain Language

The paper is a placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1997 (Alcohol and alcoholism (Oxford, Oxfordshire)), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.