Influence of endogenous cholinergic tone and growth hormone-releasing peptide-6 on exercise induced growth hormone release

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRP-6, published as a randomized controlled trial.

The neuroendocrine mechanisms of exercise-induced GH release remain incompletely understood.

In this study the researchers have investigated the influence of endogenous cholinergic tone and growth hormone-releasing peptide-6 (GHRP-6) on exercise induced GH release.

Who Took Part

By PubMed's age tags, the people studied were adults, men only.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

An indirect estimation of the secretory pattern of GH was calculated by the deconvolution technique.

The five tests were performed in random order after an overnight fast, and at least 3 days apart.

Serial blood samples from an indwelling catheter were taken before, during and after exercise for analysis of GH (IRMA), lactate (YSI 2300) and haematocrit (micromethod).

What Was Measured

The subject headings attached to it are Cholinesterase Inhibitors, Exercise, Growth Hormone, Growth Hormone-Releasing Hormone, Hematocrit, Lactic Acid and Oligopeptides.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRP-6.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 1997 (Clinical endocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the GHRP-6 compound page, all human trials.