The effect of growth hormone (GH) on histomorphometric indices of bone structure and bone turnover in GH-deficient men.

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

The researchers investigated the effects of GH on bone structure and turnover by histomorphometry in GH-deficient adults.

Thirteen patients had isolated GH deficiency and 23 patients had multiple pituitary hormone deficiencies.

Who Took Part

The abstract describes 23 patients taking part.

By PubMed's age tags, the people studied were adults, men only.

How the Study Was Run

The design is described as randomized and placebo-controlled.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Some patients received a placebo instead of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), giving a reference point.

What Was Measured

The subject headings attached to it are Bone Density, Bone Remodeling, Bone Resorption, Bone and Bones, Growth Hormone, Human Growth Hormone and Insulin-Like Growth Factor I.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 23 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1997 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.