The effect of vitamin D supplementation on the bone mineral density of the femoral neck is associated with vitamin D receptor genotype.

What Was Tested

Researchers studied Calcium, Dietary in this randomized controlled trial publication.

In this study, the researchers examined the effect of vitamin D3 supplementation on BMD at the femoral neck in relation to VDR genotype.

VDR genotype was based on the presence (b) or absence (B) of the BsmI restriction site.

Who Took Part

The study group was 81 women.

By PubMed's age tags, the people studied were older adults and people over 80, women only.

How the Study Was Run

The design is described as randomized and placebo-controlled.

The women were allocated by chance, so the Calcium, Dietary group and the comparison group should start out alike.

The comparison arm used a placebo, so changes seen with Calcium, Dietary could be set against what happens without it.

Mean BMD of the right and left femoral neck was measured at baseline and after 1 and 2 years.

What Was Measured

Topics PubMed links to this paper include Absorptiometry, Photon, Biomarkers, Body Mass Index, Bone Density, Calcium, Dietary, Cholecalciferol and Femoral Neck Fractures.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Calcium, Dietary in 81 women.

The publication is from 1997 (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research), a journal based in England.

More context: all human trials.