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Growth hormone treatment of short children born small-for-gestational-age: the Nordic Multicentre Trial.

Plain-language guide to PMID 9560030 (1998): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 children.

Key Facts

PMID
9560030
Journal
Acta paediatrica (Oslo, Norway : 1992)
Year
1998
Study type
Randomized Controlled Trial
Authors
Boguszewski M et al. (12 authors)
DOI
10.1080/08035259850157282

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

In total 42 children completed 2 y of follow-up, and 24 children from the treated groups completed 3 y of treatment.

Their mean (SD) age at the start of the study was 4.69 (1.61) y and their mean (SD) height was -3.16 (0.70) standard deviation scores (SDS).

Who Took Part

The abstract describes 12 children taking part.

PubMed indexes the participants as infants and young children, both men and women.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

Their mean (SD) age at the start of the study was 4.69 (1.61) y and their mean (SD) height was -3.16 (0.70) standard deviation scores (SDS).

The subject headings attached to it are Body Height, Denmark, Finland, Growth Disorders, Human Growth Hormone, Infant, Small for Gestational Age and Statistics, Nonparametric.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 children.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1998 (Acta paediatrica (Oslo, Norway : 1992)), a journal based in Norway.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.