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Cognitive changes during growth hormone replacement in adult men.

Plain-language guide to PMID 9618751 (1998): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 48 men.

Key Facts

PMID
9618751
Journal
Psychoneuroendocrinology
Year
1998
Study type
Randomized Controlled Trial
Authors
Deijen JB et al. (3 authors)
DOI
10.1016/s0306-4530(97)00092-9

What This Study Did, in Plain Language

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.

The present study evaluates the effects of 2 years of growth hormone (GH) replacement therapy on psychological well-being and cognitive performance in adults with childhood-onset growth hormone deficiency (CO-GHD).

Psychological assessments were made every 6 months.

Who Took Part

According to the abstract, 48 men were involved.

By PubMed's age tags, the people studied were adults, men only.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

What Was Measured

The present study evaluates the effects of 2 years of growth hormone (GH) replacement therapy on psychological well-being and cognitive performance in adults with childhood-onset growth hormone deficiency (CO-GHD).

Psychological assessments were made every 6 months.

PubMed files the paper under topics including Affect, Cognition, Growth Hormone, Insulin-Like Growth Factor I, Memory, Pituitary Hormones and Psychological Tests.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 48 men.

The publication is from 1998 (Psychoneuroendocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.