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Induction of labor by intracervical prostaglandin gel and oxytocin infusion in primigravid women with unfavorable cervix
Plain-language guide to PMID 9621474 (1997): randomized controlled trial of Oxytocin.
Key Facts
- PMID
- 9621474
- Journal
- Bangladesh Medical Research Council bulletin
- Year
- 1997
- Study type
- Randomized Controlled Trial
- Authors
- Ashrafunnessa et al. (6 authors)
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Oxytocin, published as a randomized controlled trial.
The rate of Cesarean Section for failed induction of labor and maternal and fetal compilations are high when labor is induced in a nulliparas women with an unripe cervix by amniotomy and oxytocin infusion.
A prospective randomized trial was performed on one hundred primigravid women between 37 and 42 weeks of gestation with singleton pregnancy, cephalic presentation and unfavorable cervix (Modified Bishop Score < or = 5) in the department of Obstetrics & Gynaecology of Institute of Postgraduate Medicine & Research from 1st May 1996 to 30th April 1997.
Who Took Part
By PubMed's age tags, the people studied were adults, women only.
In this study the efficiency of prostaglandin E2 intracervical (PGE2 IC) gel in induction of labor in a group of primigravid women with unripe cervix was assessed and compared with another group with similar characteristics using oxytocin infusion and artificial rupture of membrane (ARM).
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
A prospective randomized trial was performed on one hundred primigravid women between 37 and 42 weeks of gestation with singleton pregnancy, cephalic presentation and unfavorable cervix (Modified Bishop Score < or = 5) in the department of Obstetrics & Gynaecology of Institute of Postgraduate Medicine & Research from 1st May 1996 to 30th April 1997.
The subject headings attached to it are Cesarean Section, Premature Rupture of Fetal Membranes, Gels, Gestational Age, Labor, Induced, Oxytocin and Parity.
What This Means in Plain Language
The paper is a randomized study of Oxytocin.
The publication is from 1997 (Bangladesh Medical Research Council bulletin), a journal based in Bangladesh.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.