Calcium supplementation suppresses bone turnover during weight reduction in postmenopausal women.

What Was Tested

Researchers studied Calcium, Dietary in this randomized controlled trial publication.

Bone mobilization, lowering of bone mineral density (BMD), and osteoporotic fractures are recognized in postmenopausal women with weight loss.

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, women only.

Body weight, bone turnover markers (pyridinium cross-links), osteocalcin, and parathyroid hormone (PTH) were measured at treatment weeks 1-5, 7, 10, 13, 16, 20, and 25.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Calcium, Dietary group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Calcium, Dietary.

The comparison arm used a placebo, so changes seen with Calcium, Dietary could be set against what happens without it.

Total body BMD, insulin-like growth factor, 25-hydroxyvitamin D, and sex hormone binding globulin (SHBG) were measured at baseline and week 25.

What Was Measured

PubMed files the paper under topics including Bone Density, Bone Resorption, Calcium, Dietary, Dietary Supplements, Osteocalcin, Parathyroid Hormone and Pyridinium Compounds.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Calcium, Dietary.

The publication is from 1998 (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research), a journal based in England.

More context: all human trials.