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Copolymer-1 in the treatment of multiple sclerosis
Plain-language guide to PMID 9642622 (1998): double-blind randomized controlled trial study of Glatiramer Acetate in 251 patients, multiple sclerosis.
Key Facts
- PMID
- 9642622
- Journal
- The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
- Year
- 1998
- Study type
- Randomized Controlled Trial
- Authors
- Boyden KM
- DOI
- 10.1097/01376517-199804000-00008
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Glatiramer Acetate in the context of multiple sclerosis, published as a randomized controlled trial.
Recent research in the treatment of multiple sclerosis (MS) has yielded new therapies.
Who Took Part
The abstract describes 251 patients taking part.
How the Study Was Run
The design is described as randomized, double-blind, placebo-controlled and multicenter.
The patients were allocated by chance, so the Glatiramer Acetate group and the comparison group should start out alike.
As a double-blind Glatiramer Acetate study, the assignments were hidden from both participants and investigators until the end.
Some patients received a placebo instead of Glatiramer Acetate, giving a reference point.
More than one site took part, so the patients came from several places.
What Was Measured
PubMed files the paper under topics including Glatiramer Acetate, Immunosuppressive Agents, Multiple Sclerosis and Peptides.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Glatiramer Acetate in 251 patients in people with multiple sclerosis.
The publication is from 1998 (The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses), a journal based in United States.
More context: the Glatiramer Acetate compound page, Multiple sclerosis research.
Our Notes on the Compound
Glatiramer Acetate: A mix of synthetic amino-acid chains (Copaxone) used in relapsing multiple sclerosis.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.