Increased physical activity and the growth hormone-IGF-I axis in adolescent males.

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Before and after the intervention, the researchers measured thigh muscle volume using magnetic resonance imaging and serum levels of mean growth hormone (GH) by overnight multiple sampling, GH binding protein (GHBP), IGF-I, and IGFBPs 1-5 by standard assays.

Who Took Part

According to the abstract, 38 subjects were involved.

The age groups tagged for this paper are teenagers, men only.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Energy expenditure was assessed with the doubly labeled water technique toward the end of the study.

What Was Measured

Before and after the intervention, the researchers measured thigh muscle volume using magnetic resonance imaging and serum levels of mean growth hormone (GH) by overnight multiple sampling, GH binding protein (GHBP), IGF-I, and IGFBPs 1-5 by standard assays.

The subject headings attached to it are Circadian Rhythm, Energy Metabolism, Exercise, Human Growth Hormone, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I and Insulin-Like Growth Factor II.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 38 subjects.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1998 (The American journal of physiology), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.