Induction of labor with misoprostol for premature rupture of membranes beyond thirty-six weeks' gestation

What Was Tested

Researchers studied Oxytocin in this randomized controlled trial publication.

Their purpose was to compare vaginally administered misoprostol (Cytotec) with intravenous oxytocin for labor induction in women with premature rupture of membranes beyond 36 weeks' gestation.

Who Took Part

PubMed tags the participants as women only.

Two hundred subjects with rupture of membranes without labor were randomly assigned to receive vaginally administered misoprostol or intravenous oxytocin.

How the Study Was Run

The design is described as randomized.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Twenty-five micrograms of misoprostol (Cytotec) was placed in the posterior vaginal fornix.

What Was Measured

The subject headings attached to it are Administration, Intravaginal, Premature Rupture of Fetal Membranes, Labor, Induced, Misoprostol, Oxytocics, Oxytocin and Pregnancy Outcome.

The authors tagged it with the keywords Americas, Biology, Comparative Studies, Delivery, Developed Countries and Endocrine System.

What This Means in Plain Language

The paper is a randomized study of Oxytocin.

Its findings take up roughly 10 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1998 (American journal of obstetrics and gynecology), a journal based in United States.

More context: the Oxytocin compound page, all human trials.