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Effects of magnesium supplementation in hypertensive patients: assessment by office, home, and ambulatory blood pressures.

Plain-language guide to PMID 9719052 (1998): crossover randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 34 men, low blood pressure and orthostatic hypotension.

Key Facts

PMID
9719052
Journal
Hypertension (Dallas, Tex. : 1979)
Year
1998
Study type
Randomized Controlled Trial
Authors
Kawano Y et al. (4 authors)
DOI
10.1161/01.hyp.32.2.260

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension, published as a randomized controlled trial.

However, the results of clinical studies are inconsistent.

In the control period, office, home, and average 24-hour BPs (mean+/-SE) were 148.6+/-1.6/90.0+/-0.9, 136.4+/-1.3/86.8+/-0.9, and 133.7+/-1.3/81.0+/-0.8 mmHg, respectively.

Who Took Part

According to the abstract, 34 men were involved.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

How the Study Was Run

The design is described as randomized and crossover.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

In the crossover set-up each of the men took both Vitamin D, K2, Magnesium and Zinc and the comparison in turn, acting as their own control.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Blood Pressure Monitoring, Ambulatory, Hypertension and Magnesium.

What This Means in Plain Language

The paper is a randomized and crossover study of Vitamin D, K2, Magnesium and Zinc in 34 men in people with low blood pressure and orthostatic hypotension.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1998 (Hypertension (Dallas, Tex. : 1979)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.