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Recombinant human growth hormone therapy in malnourished dialysis patients: a randomized controlled study.

Plain-language guide to PMID 9740162 (1998): pilot randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 6 women.

Key Facts

PMID
9740162
Journal
American journal of kidney diseases : the official journal of the National Kidney Foundation
Year
1998
Study type
Randomized Controlled Trial
Authors
Iglesias P et al. (9 authors)
DOI
10.1053/ajkd.1998.v32.pm9740162

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

The aim of the present study was to assess the effects of rhGH on nutritional status in a group of malnourished adult chronic dialysis patients undergoing both continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD).

Why It Was Studied

However, up-to-date, comparative studies with control groups of dialysis patients have not been reported.

The patients were randomly assigned to the control group (nine patients; 6 women, 3 men; mean age, 58.3 +/- 5.6 years; seven undergoing CAPD, two undergoing HD) or the rhGH group (eight patients; three women, five men; mean age, 63.9 +/- 3.1 years; four undergoing CAPD, four undergoing HD).

Who Took Part

According to the abstract, 6 women were involved.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

How the Study Was Run

In design terms this was a randomized and pilot study.

The women were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

It is described as a pilot, a small early test of whether a larger Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study would be practical.

What Was Measured

Topics PubMed links to this paper include Blood Urea Nitrogen, Growth Hormone, Insulin-Like Growth Factor I, Kidney Failure, Chronic, Nutritional Status, Peritoneal Dialysis, Continuous Ambulatory and Pilot Projects.

What This Means in Plain Language

The paper is a randomized and pilot study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 6 women.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1998 (American journal of kidney diseases : the official journal of the National Kidney Foundation), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.