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Growth hormone binding protein activity in obese children.
Plain-language guide to PMID 9766258 (1998): clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 boys.
Key Facts
- PMID
- 9766258
- Journal
- Journal of endocrinological investigation
- Year
- 1998
- Study type
- Clinical Trial
- Authors
- Seminara S et al. (8 authors)
- DOI
- 10.1007/BF03347323
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a clinical trial.
The researchers evaluated growth hormone binding protein (GHBP) activity in a group of obese children (12 boys and 12 girls, age 3.1-14.7 years, BMI 21.1-33.3, 11 prepubertal and 13 early pubertal) and in 26 age-matched normal weight children (14 boys and 12 girls, age 2.1-16.0 years, BMI 14.2-21.4, 18 prepubertal and 8 early pubertal).
All children were of normal stature.
Who Took Part
According to the abstract, 12 boys were involved.
PubMed indexes the participants as young children, children and teenagers, both men and women.
What Was Measured
The researchers evaluated growth hormone binding protein (GHBP) activity in a group of obese children (12 boys and 12 girls, age 3.1-14.7 years, BMI 21.1-33.3, 11 prepubertal and 13 early pubertal) and in 26 age-matched normal weight children (14 boys and 12 girls, age 2.1-16.0 years, BMI 14.2-21.4, 18 prepubertal and 8 early pubertal).
Topics PubMed links to this paper include Area Under Curve, Body Mass Index, Carrier Proteins, Glucose Tolerance Test, Human Growth Hormone, Insulin and Obesity.
What This Means in Plain Language
This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 boys.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 1998 (Journal of endocrinological investigation), a journal based in Italy.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.