The effects of calcium supplementation, duration of lactation, and time of day on concentrations of parathyroid hormone-related protein in human milk: a pilot study.

What Was Tested

This randomized controlled trial looks at Parathyroid Hormone (PTH 1-84).

This pilot study reports parathyroid hormone-related protein (PTHrP) in milk from 14 women (placebo = 6, calcium = 8) over the duration of lactation.

Milk samples collected 0 to 250 days postpartum were assayed for PTHrP by a two-site immunoradiometric assay.

Who Took Part

According to the abstract, 14 women were involved.

The age groups tagged for this paper are adults, women only.

How the Study Was Run

The design is described as randomized, placebo-controlled and pilot.

Because people in this Parathyroid Hormone (PTH 1-84) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Parathyroid Hormone (PTH 1-84) could be set against what happens without it.

It is described as a pilot, a small early test of whether a larger Parathyroid Hormone (PTH 1-84) study would be practical.

What Was Measured

Topics PubMed links to this paper include Calcium, Calcium, Dietary, Circadian Rhythm, Colostrum, Lactation, Milk, Human and Parathyroid Hormone-Related Protein.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and pilot study of Parathyroid Hormone (PTH 1-84) in 14 women.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 1998 (Journal of human lactation : official journal of International Lactation Consultant Association), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.