Calcium and vitamin D supplementation increases spinal BMD in healthy, postmenopausal women.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers undertook a double-masked, randomized, placebo-controlled trial to evaluate the effect of a calcium and vitamin D supplement and a calcium supplement plus multivitamins on bone loss at the hip, spine and forearm.

Why It Was Studied

The study was performed in 240 healthy women, 58-67 years of age.

Duration of treatment was 2 years.

Who Took Part

The study group was 240 women.

The age groups tagged for this paper are middle-aged adults and older adults, women only.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The women were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Bone mineral density (BMD) was measured at the lumbar spine, hip and forearm.

What Was Measured

PubMed files the paper under topics including Bone Density, Calcium, Cholecalciferol, Lumbar Vertebrae, Osteoporosis, Postmenopausal and Parathyroid Hormone.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 240 women.

The publication is from 1998 (Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.