Transfer of frozen-thawed embryos in artificially prepared cycles with and without prior gonadotrophin-releasing hormone agonist suppression: a prospective randomized study.

What Was Tested

Researchers studied Progesterone in this randomized controlled trial publication.

Transfer of frozen-thawed embryos is usually carried out in a natural cycle or in a programmed cycle in which the endometrium is exogenously stimulated following down-regulation of the hypophysis.

To analyse the possibility that the programmed cycle for embryo transfer can still be hormonally manipulated without the use of gonadotrophin-releasing hormone agonist (GnRHa) the researchers have conducted a prospective randomized study that compared the outcome of frozen-thawed embryo transfer cycles using micronized 17beta-oestradiol and micronized progesterone preparations with and without the concomitant use of GnRHa.

Who Took Part

The abstract describes 53 patients taking part.

PubMed indexes the participants as adults, women only.

How the Study Was Run

The design is described as randomized.

Because people in this Progesterone study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

To analyse the possibility that the programmed cycle for embryo transfer can still be hormonally manipulated without the use of gonadotrophin-releasing hormone agonist (GnRHa) the researchers have conducted a prospective randomized study that compared the outcome of frozen-thawed embryo transfer cycles using micronized 17beta-oestradiol and micronized progesterone preparations with and without the concomitant use of GnRHa.

The subject headings attached to it are Cryopreservation, Embryo Transfer, Estradiol, Fertility Agents, Female, Gonadotropin-Releasing Hormone, Pregnancy Outcome and Progesterone.

What This Means in Plain Language

The paper is a randomized study of Progesterone in 53 patients.

The publication is from 1998 (Human reproduction (Oxford, England)), a journal based in England.

More context: all human trials.