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Plasma leptin levels in trauma patients: effect of adjuvant recombinant human growth hormone in intravenously fed multiple trauma patients.

Plain-language guide to PMID 9829605 (1999): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 14, men.

Key Facts

PMID
9829605
Journal
JPEN. Journal of parenteral and enteral nutrition
Year
1999
Study type
Randomized Controlled Trial
Authors
Jeevanandam M et al. (3 authors)
DOI
10.1177/0148607198022006340

What This Study Did, in Plain Language

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.

Leptin, the newly discovered ob gene product, is synthesized primarily in adipose tissue and circulates to all parts of the body.

Who Took Part

The abstract describes 14, men taking part.

The age groups tagged for this paper are teenagers, adults, middle-aged adults and older adults, both men and women.

The nutritional influence on plasma leptin in these patients was monitored during the subsequent 7 days of total parenteral nutrition (TPN).

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

What Was Measured

Topics PubMed links to this paper include Basal Metabolism, Blood Glucose, Growth Hormone, Injury Severity Score, Insulin, Leptin and Multiple Trauma.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 14, men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1999 (JPEN. Journal of parenteral and enteral nutrition), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.