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[Vitamin D status in the adolescent: seasonal variations and effects of winter supplementation with vitamin D3].
Plain-language guide to PMID 9853057 (1998): clinical trial of Vitamin D, K2, Magnesium and Zinc in 24 adolescents.
Key Facts
- PMID
- 9853057
- Journal
- Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
- Year
- 1998
- Study type
- Clinical Trial
- Authors
- Guillemant J et al. (5 authors)
- DOI
- 10.1016/s0929-693x(98)81235-9
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this clinical trial publication.
The aim of the present study was to test the biological effects of a treatment with vitamin D3 during winter.
Why It Was Studied
Recently, 25 hydroxyvitamin D (25 OHD) blood concentrations measured in adolescents during or at the end of winter were found very low.
A concomitant stimulation of parathyroid function was observed.
Who Took Part
According to the abstract, 24 adolescents were involved.
The age groups tagged for this paper are teenagers, men only.
How the Study Was Run
They were pupils in a lad-jockeys training center located in the countryside near Chantilly (49 degrees northern latitude).
Blood concentrations of 25 OHD, calcium and intact parathormone (PTH) were measured three times: before each oral intake of vitamin D3 and 2 months after the last intake (March).
A group of 32 male adolescents (mean age +/- SD: 14 y 9 m +/- 6 m), pupils in the same center, receiving no vitamin D and sampled in November and in March, served as controls.
What Was Measured
Recently, 25 hydroxyvitamin D (25 OHD) blood concentrations measured in adolescents during or at the end of winter were found very low.
PubMed files the paper under topics including Cholecalciferol, Cross-Sectional Studies, France, Incidence, Seasons and Vitamin D Deficiency.
What This Means in Plain Language
This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 24 adolescents.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 1998 (Archives de pediatrie : organe officiel de la Societe francaise de pediatrie), a journal based in France.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.