Postprandial lipid, glucose, insulin, and cholecystokinin responses in men fed barley pasta enriched with beta-glucan

What Was Tested

This randomized controlled trial paper looks at Cholecystokinin (CCK).

The researchers investigated in 11 healthy men the response of insulin, glucose, cholecystokinin, and lipid to 2 test meals containing beta-glucan.

Why It Was Studied

Fiber regulates the rate and site of lipid and carbohydrate digestion and absorption and thus can modify the alimentary responses to a meal.

When fiber sources containing viscous polysaccharides are included in a meal, a slower rate of carbohydrate and lipid absorption will modify the alimentary hormone and lipid responses.

Who Took Part

According to the abstract, 11 men were involved.

PubMed indexes the participants as adults, men only.

How the Study Was Run

The design is described as randomized and crossover.

The men were allocated by chance, so the Cholecystokinin (CCK) group and the comparison group should start out alike.

Each person switched between Cholecystokinin (CCK) and the comparison at some point, usually with a gap in between.

The low-fiber meal contained pasta made with wheat flour.

What Was Measured

PubMed files the paper under topics including Analysis of Variance, Blood Glucose, Cholecystokinin, Dietary Fiber, Glucans, Hordeum and Insulin.

What This Means in Plain Language

The paper is a randomized and crossover study of Cholecystokinin (CCK) in 11 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1999 (The American journal of clinical nutrition), a journal based in United States.

More context: the Cholecystokinin (CCK) compound page, all human trials.